New brain cancer drug shows promise in early trial for patients with IDH1 mutation
NCT ID NCT02704858
First seen Jan 05, 2026 · Last updated May 14, 2026 · Updated 20 times
Summary
This study tests a drug called NEO100 (perillyl alcohol) in about 49 people with a specific type of aggressive brain cancer (grade III or IV glioma) that has an IDH1 mutation and has returned or worsened. The goal is to find the safest dose and see if it helps people live longer. Participants take the drug four times a day in 28-day cycles until their disease gets worse or they stop for other reasons.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atlantic Health (Overlook Medical Center)
RECRUITINGSummit, New Jersey, 07901, United States
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Baylor Scott & White Health
RECRUITINGDallas, Texas, 75061, United States
Contact Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44333, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Georgia Cancer Center (Augusta University)
RECRUITINGAugusta, Georgia, 30912, United States
Contact
Contact Email: •••••@•••••
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Northwell Health
RECRUITINGNew York, New York, 10016, United States
Contact Email: •••••@•••••
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Ochsner Health
RECRUITINGNew Orleans, Louisiana, 70121, United States
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Saint John Cancer Institute
RECRUITINGSanta Monica, California, 90404, United States
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University of Southern California
RECRUITINGLos Angeles, California, 90033, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75235, United States
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University of Washington Medical Center
NOT_YET_RECRUITINGSeattle, Washington, 98105, United States
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University of Wisconsin Hospital and Clinic
NOT_YET_RECRUITINGMadison, Wisconsin, 53792, United States
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Wake Forest University Health Sciences
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Conditions
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