Exercise during chemo may boost tumor shrinkage in breast cancer
NCT ID NCT04623554
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a supervised exercise program (a mix of high-intensity cycling and strength training) done three times a week during chemotherapy can help shrink breast tumors and improve how much chemo patients can tolerate. About 100 women with breast cancer will be randomly assigned to either the exercise program or usual care. The main goal is to see if exercise leads to a greater reduction in tumor size measured by MRI.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- supervised aerobic and resistance exercise program
- What this could lead to
- If it works, this could show that regular exercise during chemotherapy helps shrink breast tumors and allows patients to complete more of their planned treatment.
- What could go wrong
- This is a small, early-stage trial (102 people) looking at tumor size on MRI, not long-term survival. Exercise may not significantly affect tumor response, and results may not apply to all breast cancer patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Clinical Oncology and Palliative Care, Zealand University Hospital
Næstved, Denmark
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