Last-Resort drug access opens for ALK-Positive cancer patients

NCT ID NCT06834074

AVAILABLE Disease control Sponsor: Nuvalent Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This program offers early access to the investigational drug neladalkib for people with advanced ALK-positive lung cancer or other ALK-positive solid tumors who have run out of standard treatment options and cannot join a clinical trial. Participants must be at least 18 years old and have already tried at least one ALK-targeted therapy. The goal is to provide a potential treatment option when no others are available.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALK-POSITIVE NON-SMALL CELL LUNG CANCER (NSCLC) NON-SMALL CELL LUNG CANCER

Contacts and locations

Locations

AUSL della Romagna - Ravenna
AVAILABLE

Ravenna, 48121, Italy
Antoni van Leeuwenhoek Hospital
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Amsterdam, 1006 BE, Netherlands
Azienda Ospedaliero Universitaria delle Marche
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Ancona, 60126, Italy
BC Cancer - Vancouver
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Vancouver, British Columbia, V5Z 4E6, Canada
CHU de Nantes
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Nantes, Pays de la Loire Region, 44800, France
Centre Leon Berard
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Lyon, Auvergne-Rhône-Alpes, 69008, France
Chung Shan Medical University
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Taichung, 402306, Taiwan
Cross Cancer Institute
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Edmonton, Alberta, AB T6G 1Z2, Canada
Dana-Farber Cancer Institute
AVAILABLE

Boston, Massachusetts, 02215, United States
Duke University
AVAILABLE

Durham, North Carolina, 27708, United States
Fondazione IRCCS Istituto Nazionale dei Tumori
AVAILABLE

Milan, 20133, Italy
GCS IUCT Oncopole
AVAILABLE

Toulouse, Occitanie, 31059, France
Gerencia de Gestión Integrada A Coruna
AVAILABLE

A Coruña, 15006, Spain
Henry Ford Cancer Institute
AVAILABLE

Detroit, Michigan, 48202, United States
Hospital Universitario 12 de Octubre
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Madrid, 28041, Spain
Hospital Universitario Vall d'Hebron
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Barcelona, 08035, Spain
IRCCS Istituto Nazionale Tumori Regina Elena
AVAILABLE

Rome, 53, Italy
IRCCS Istituto Oncologico Veneto
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Padova, 35128, Italy
Institut Gustave Roussy
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Villejuif, Île-de-France Region, 94800, France
Kantonsspital Luzern
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Lucerne, 6000, Switzerland
L'Istituto Europeo di Oncologia S.r.l.
AVAILABLE

Milan, 20141, Italy
Massachusetts General Hospital
AVAILABLE

Boston, Massachusetts, 02114, United States
Memorial Sloan Kettering Cancer Center
AVAILABLE

New York, New York, 10065, United States
NYU Langone Health
AVAILABLE

New York, New York, 10016, United States
National Cancer Centre Singapore
AVAILABLE

Singapore, 168583, Singapore
National Cheng-Kung University Hospital
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Tainan, 704, Taiwan
National Taiwan University Hospital
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Taipei, 100, Taiwan
National University Hospital Singapore
AVAILABLE

Singapore, 119074, Singapore
Ospedale Italiano di Lugano
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Viganello, 6962, Switzerland
Peter MacCallum Cancer Centre
AVAILABLE

Melbourne, Victoria, 3000, Australia
Princess Margaret Hospital
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Toronto, Ontario, ON M5G 2M9, Canada
Royal North Shore Hospital
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St Leonards, New South Wales, 2065, Australia
Seoul National University Hospital
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Seoul, Jongno-gu, 03080, South Korea
Stichting Het Nederlands Kanker Instituut
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Amsterdam, North Holland, 1066 CX, Netherlands
The Christie Hospital
AVAILABLE

Manchester, M20 4BX, United Kingdom
The Ohio State University
AVAILABLE

Columbus, Ohio, 43210, United States
The Ottawa Hospital
AVAILABLE

Ottawa, Ontario, K1H 8L6, Canada
The Royal Marsden Hospital
AVAILABLE

Sutton, Surrey, SM2 5PT, United Kingdom
The Royal Marsden Hospital
AVAILABLE

London, UK, SW3 6JJ, United Kingdom
The University of Texas MD Anderson Cancer Center
AVAILABLE

Houston, Texas, 77030, United States
University Medical Center Groningen
AVAILABLE

Groningen, 9713 GZ, Netherlands
University Of California Irvine Medical Center
AVAILABLE

Orange, California, 92868, United States
University of Chicago Medical Center
AVAILABLE

Chicago, Illinois, 60637, United States
University of Colorado Anschutz School of Medicine
AVAILABLE

Aurora, Colorado, 80045, United States
University of Washington / Fred Hutchinson Cancer Center
AVAILABLE

Seattle, Washington, 98109, United States
Uomi Cancer Center-Clinica Tres Torres
AVAILABLE

Barcelona, 08017, Spain
Washington University in St. Louis
AVAILABLE

St Louis, Missouri, 63110, United States

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