New drug combo may cut opioid use in ICU patients
NCT ID NCT05071352
First seen Jan 04, 2026 · Last updated May 13, 2026 · Updated 16 times
Summary
This study tested whether adding a painkiller called nefopam to standard care could lower the amount of strong opioids needed by ICU patients on breathing machines. 60 adults were randomly assigned to receive either nefopam or a placebo alongside usual sedation. The goal was to see if nefopam could safely reduce opioid use while keeping patients comfortable and calm.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Cairo University Hospitals (Kasr Alainy)
Cairo, Egypt
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