Tiny camera could make knee surgery less painful

NCT ID NCT07823504

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers compare two ways to perform knee surgery for simple problems like meniscal tears, cartilage damage, and loose bodies. One method uses a needle arthroscopy with a 1.9mm camera through tiny openings, and the other uses standard arthroscopy. Adults aged 18 to 65 join the study, and researchers track their pain, opioid use, recovery, and return to activity over three months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
needle arthroscopy using a 1.9mm camera system called NanoScope
What this could lead to
If needle arthroscopy works as well as standard surgery, people with simple knee problems could recover with less pain and smaller scars.
What could go wrong
This is a small pilot trial of 54 people, so it may not show a clear difference between the two techniques. Needle arthroscopy may not work for every knee problem, and some patients may still need standard surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 54 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Clinical diagnosis of: Meniscal tears (Medial or Lateral) suitable for partial meniscectomy or simple repair; Chondral lesions / Chondromalacia (ICRS Grade 1-3); Loose bodies; Synovitis requiring synovectomy; Cyclops lesion (post-ACL reconstruction). * Age: 18 to 65 years at time of surgery. * Imaging: Pre-operative MRI performed within 6 months of the surgery date. And an X-ray showing no fractures. * Consent: Willingness and ability to provide informed consent and attend follow-up visits. Exclusion Criteria: * • Instability: Concomitant ACL, PCL, or multi-ligament injury requiring reconstruction (reconstruction cannot be performed solely with NanoScope). * Osteoarthritis: Advanced Osteoarthritis defined as Kellgren-Lawrence Grade 3 or 4 (bone-on-bone) on pre-operative weight-bearing radiographs. * Complex Pathology: Complex meniscal tears requiring repair techniques strictly requiring standard instrumentation (e.g., large bucket-handle tears requiring inside-out/outside-in sutures). * Infection: Active local or systemic infection. * BMI: Body Mass Index \> 40 (due to potential visualization difficulties with the 1.9mm system in deep soft tissue). * Previous Surgery: Revision meniscal repair on the affected compartment (unless simple debridement). * Legal/WCB: Patients involved in active litigation or Workers Compensation Board (WCB) claims. * Language: Unable to speak, read, or understand English (preventing completion of PROMs). * Pregnancy: at the time of surgery. * Mental Health: Conditions that preclude informed consent and follow-up (e.g. mental capacity, impaired judgment and/or memory, severe mood episodes, dementia, etc). * Major illness: Life expectancy \<1yr or unacceptably high surgery risk). Intra-operative exclusions: Final assessment of eligibility will be made intra-operatively and include: * Arthritis: If grade 3 or 4 chondral damage (exposed bone) is discovered intra-operatively that was not evident on radiographs, the patient may be excluded from the per-protocol analysis but retained for safety analysis. * Technique Failure (Crossover): If a patient randomized to the NanoScope Group has pathology that cannot be adequately visualized or treated with the needle system (e.g., tight compartment, excessive bleeding, or inability to access pathology), the surgeon will convert to Conventional Arthroscopy. These patients will be considered "enrolled" and analyzed in their original randomized group (Intention-to-Treat principle), but the case will be documented as a "Failure of Technique".

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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