Experimental combo for tough head and neck cancer shows promise but trial ends early

NCT ID NCT04862455

First seen Nov 21, 2025 · Last updated Jun 12, 2026 · Updated 23 times

Summary

This study tested a new treatment for head and neck cancer that has come back or spread. It combined a drug called NBTXR3 (activated by radiation) with the immunotherapy pembrolizumab. The goal was to see if this combination could shrink tumors and help patients live longer. The trial was terminated early after enrolling only 14 people, so results are limited.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.