GPS for surgeons: new navigation tool aims to improve head and neck cancer outcomes

NCT ID NCT05671458

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a navigation system that helps surgeons remove head and neck tumors more precisely. During surgery, the system creates a 3D map of the tumor and its edges, which is then used to plan follow-up radiation therapy. The goal is to reduce the chance of leftover cancer cells and improve local control. The trial will enroll 60 patients with midface or skull-base tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
intraoperative navigation and tumor resection maps
What this could lead to
If successful, this could make head and neck cancer surgery more precise, reducing the chance of leftover tumor and improving radiotherapy planning.
What could go wrong
This is a small early-phase trial with only 60 participants, so results may not apply to everyone. The technique is new and its benefit over standard surgery is not yet proven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Radiotherapy, University of Heidelberg

    RECRUITING

    Heidelberg, 69120, Germany

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Other studies related to the condition(s) this trial covers.