Small study tests drug for rare, Life-Threatening skin condition

NCT ID NCT02987257

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a drug called etanercept against a placebo for people with severe skin reactions (Stevens-Johnson syndrome and toxic epidermal necrolysis). Only 2 adults took part. The goal was to see if the drug speeds up skin healing and to learn more about the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

etanercept

What this could lead to

If it works, this could point toward a better treatment for severe skin reactions like Stevens-Johnson syndrome.

What could go wrong

This trial was very small (only 2 participants) and completed, so results may not apply widely. Etanercept can increase infection risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Drug-Related Side Effects and Adverse Reactions Stevens-Johnson syndrome toxic epidermal necrolysis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University at Grady Memorial Hospital

    Atlanta, Georgia, 30303, United States

  • Johns Hopkins Bayview Medical Center

    Baltimore, Maryland, 21224, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60153, United States

  • MedStar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • University of California, Davis Medical Center

    Sacramento, California, 95817, United States

  • University of Florida Health Burn Center

    Gainesville, Florida, 32610, United States

  • University of Miami, Ryder Trauma Center

    Miami, Florida, 33136, United States

  • University of Tennessee Health Sciences Center

    Memphis, Tennessee, 38103, United States

  • University of Texas Medical Branch

    Galveston, Texas, 77555, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Washington, Harborview Medical Center

    Seattle, Washington, 98104, United States

  • Valleywise Health Medical Center

    Phoenix, Arizona, 85008, United States

  • Vanderblt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wayne State University

    Detroit, Michigan, 48201, United States