New drug trial targets scarring in fatty liver disease

NCT ID NCT05583344

Ongoing Disease control Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an investigational drug called GSK4532990 can reduce liver scarring and inflammation in adults with advanced NASH, a serious form of fatty liver disease. About 284 participants with confirmed liver damage will receive either the drug or a placebo for up to one year. Researchers will compare liver biopsy results before and after treatment to see if the drug helps improve liver health.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Locations

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Homewood, Alabama, 35209, United States
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Chandler, Arizona, 85224, United States
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Chandler, Arizona, 85712, United States
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Mesa, Arizona, 85381, United States
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Jonesboro, Arkansas, 72401, United States
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North Little Rock, Arkansas, 72117, United States
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Huntington Park, California, 90255, United States
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La Jolla, California, 92037, United States
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Orange, California, 92866, United States
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Poway, California, 92064, United States
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Rialto, California, 92377, United States
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Sacramento, California, 95817, United States
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San Francisco, California, 94115, United States
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Santa Ana, California, 92704, United States
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Van Nuys, California, 91405, United States
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Colorado Springs, Colorado, 80907, United States
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Bradenton, Florida, 34209, United States
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Coral Gables, Florida, 33134, United States
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Fort Myers, Florida, 33907, United States
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Hallandale, Florida, 33009, United States
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Hialeah, Florida, 33016, United States
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Homestead, Florida, 33032, United States
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Jupiter, Florida, 33458, United States
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Lakewood Rch, Florida, 34211, United States
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Miami, Florida, 33122, United States
GSK Investigational Site

Miami, Florida, 33126, United States
GSK Investigational Site

Miami, Florida, 33176, United States
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Miami Lakes, Florida, 33016, United States
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West Palm Beach, Florida, 33401, United States
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Athens, Georgia, 30607, United States
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Atlanta, Georgia, 30328, United States
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Marietta, Georgia, 30060, United States
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Snellville, Georgia, 30078, United States
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Indianapolis, Indiana, 46202, United States
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South Bend, Indiana, 46635, United States
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Iowa City, Iowa, 52242, United States
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Topeka, Kansas, 66606, United States
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Bastrop, Louisiana, 71220, United States
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Marrero, Louisiana, 70072, United States
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Metairie, Louisiana, 70006, United States
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Monroe, Louisiana, 71201, United States
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Shreveport, Louisiana, 71105, United States
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Columbia, Maryland, 21045, United States
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Greenbelt, Maryland, 20770, United States
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Ann Arbor, Michigan, 48109, United States
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Southfield, Michigan, 48075, United States
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Ypsilanti, Michigan, 48197, United States
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Chesterfield, Missouri, 48038, United States
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Las Vegas, Nevada, 89106, United States
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Princeton, New Jersey, 08648, United States
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Sparta, New Jersey, 07871, United States
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New York, New York, 10029, United States
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New York, New York, 10033, United States
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New York, New York, 10075, United States
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Chapel Hill, North Carolina, 27599, United States
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Durham, North Carolina, 27710, United States
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Morehead City, North Carolina, 28557, United States
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Akron, Ohio, 44320, United States
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Springboro, Ohio, 45066, United States
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Westlake, Ohio, 44145, United States
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Lancaster, Pennsylvania, 17604-3200, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Wyomissing, Pennsylvania, 19610, United States
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Chattanooga, Tennessee, 37421, United States
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Clarksville, Tennessee, 37040, United States
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Austin, Texas, 78757, United States
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Brownsville, Texas, 78520, United States
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Dallas, Texas, 75203, United States
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Edinburg, Texas, 78539, United States
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Georgetown, Texas, 78626, United States
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Houston, Texas, 77030, United States
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Houston, Texas, 77079, United States
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Houston, Texas, 77090, United States
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San Antonio, Texas, 78215, United States
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San Antonio, Texas, 78229, United States
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Waco, Texas, 76710, United States
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West Jordan, Utah, 84088, United States
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Richmond, Virginia, 23229, United States
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Richmond, Virginia, 23236, United States
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Seattle, Washington, 98105, United States
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Buenos Aires, C1061AAS, Argentina
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Capital Federal, C1181ACH, Argentina
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Ciudad AutOnoma de Buenos Aire, 1118, Argentina
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Ciudad Autonoma de Bueno, C1056ABJ, Argentina
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Pilar, B1629AHJ, Argentina
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Rosario, 3000, Argentina
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San Miguel de Tucumán, T4000IHE, Argentina
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Nedlands, Western Australia, 6009, Australia
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Perth, Western Australia, 6000, Australia
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Brussels, 1070, Belgium
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Brussels, 1200, Belgium
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Edegem, 2650, Belgium
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Calgary, Alberta, T2N 4Z6, Canada
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Toronto, Ontario, M5G 2C4, Canada
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Angers, 49933, France
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Limoges, 87042, France
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Paris, 75651, France
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Pierre-Bénite, 69310, France
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Strasbourg, 67091, France
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Athens, 11527, Greece
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Rio Patras, 26504, Greece
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Thessaloniki, 546 42, Greece
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Thessaloniki, 54642, Greece
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Bhubaneswar, 751019, India
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Chandigarh, 160062, India
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Coimbatore, 641005, India
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Guhawati, 781006, India
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Mumbai, 400012, India
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Nagpur, 441108, India
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New Delhi, 110070, India
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Secunderabad, 500003, India
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Surat, 395009, India
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Florence, 50139, Italy
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Milan, 20122, Italy
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Modena, 41126, Italy
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Padua, 35128, Italy
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Palermo, 90127, Italy
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Roma, 00168, Italy
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Rozzano MI, 20089, Italy
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San Giovanni Rotondo FG, 71013, Italy
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Fukui, 918-8503, Japan
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Fukuoka, 830-0011, Japan
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Gifu, 500-8513, Japan
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Gifu, 500-8717, Japan
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Gifu, 501-6062, Japan
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Gifu, 503-8502, Japan
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Hiroshima, 734-8551, Japan
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Kagawa, 760-0017, Japan
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Kagawa, 760-8557, Japan
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Kagawa, 761-0793, Japan
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Kagoshima, 890-8520, Japan
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Kanagawa, 216-8511, Japan
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Kanagawa, 236-0004, Japan
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Kanagawa, 259-1143, Japan
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Nagano, 390-8621, Japan
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Nagasaki, 856-8562, Japan
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Nara, 634-8522, Japan
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Numakunai, 028-3695, Japan
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Okayama, 700-8505, Japan
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Osaka, 564-0013, Japan
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Saga, 849-8501, Japan
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Shimane, 693-8501, Japan
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Yamanashi, 409-3898, Japan
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Cuernavaca Morelos, 62170, Mexico
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Guadalajara, 44130, Mexico
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Mérida, 97070, Mexico
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Panama City, 07206, Panama
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Panama City, Panama
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San Juan, 00927, Puerto Rico
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Incheon, 22332, South Korea
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Seoul, 07061, South Korea
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Seoul, 156-755, South Korea
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Yongsan-Ku Seoul, South Korea
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Barcelona, 08035, Spain
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Madrid, 28034, Spain
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Madrid, 28041, Spain
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Madrid, 28222, Spain
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Málaga, 29010, Spain
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Sabadell Barcelona, 08208, Spain
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Santander, 39008, Spain
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Seville, 41013, Spain
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Vigo, 36071, Spain
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Ankara, 06800, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
GSK Investigational Site

Rize, 53200, Turkey (Türkiye)
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Cannock, WS11 0BN, United Kingdom
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London, SE5 9RS, United Kingdom
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Manchester, M13 9NQ, United Kingdom
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Newcastle upon Tyne, NE7 7DN, United Kingdom
GSK Investigational Site

Nottingham, NG7 2UH, United Kingdom

Conditions

Explore the condition pages connected to this study.

NON-ALCOHOLIC FATTY LIVER DISEASE NONALCOHOLIC FATTY LIVER DISEASE