Which breathing tube works best for preterm infants? a trial puts two options to the test

NCT ID NCT07725614

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial compares two common interfaces—a nasal cannula and a single nasal prong—used to deliver non-invasive breathing support to premature infants shortly after birth. Preterm babies who need help breathing will be randomly assigned to receive support through one of the two devices for one hour. The study aims to see which interface reduces the need for inserting a breathing tube, and whether one causes fewer side effects like nasal injury.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a nasal cannula or a single nasal prong as the interface for non-invasive ventilation
What this could lead to
If one interface proves better, it could reduce the need for intubation and improve breathing support for premature babies.
What could go wrong
This is a single-center trial with 140 infants, so results may not apply to all preterm populations. Both interfaces are already in use, so a clear winner is not guaranteed.

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Conditions

The condition(s) this trial relates to.

Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rumah Sakit dr. Cipto Mangunkusumo

    Jakarta, DKI Jakarta, Indonesia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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