Could a new toothpaste fix Kids' chalky teeth?

NCT ID NCT07436039

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a toothpaste made with nano-hydroxyapatite can help children aged 6-12 who have a condition called Molar-Incisor Hypomineralization (MIH), which causes weak, discolored, and sensitive teeth. Sixty children will use either the nano toothpaste or standard fluoride toothpaste for 9 months. Researchers will check if the new toothpaste reduces pain from cold air and improves tooth color compared to the standard option.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
nano-hydroxyapatite toothpaste
What this could lead to
If it works, this could offer a simple, non-invasive way to manage tooth sensitivity and discoloration in children with MIH.
What could go wrong
This is a small, early-stage trial with only 60 children, so results may not apply to everyone. The toothpaste may not outperform standard fluoride toothpaste.

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Conditions

The condition(s) this trial relates to.

Molar Hypomineralization

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • King Abdulaziz University Hospital, Jeddah, Saudi Arabia

    RECRUITING

    Jeddah, Saudi Arabia

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