Vitamin B3-like supplement studied for Alzheimer's: could it boost brain energy?

NCT ID NCT05617508

First seen Dec 11, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tested different doses of nicotinamide riboside (NR), a vitamin B3-like supplement, in 80 people with early Alzheimer's disease. The goal was to find the best dose that increases brain energy levels and changes brain metabolism safely. Participants took placebo or NR doses from 1000 mg to 3000 mg daily for 12 weeks, with brain scans and spinal fluid tests to measure effects.

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Contacts and locations

Locations

  • Haraldsplass Deaconess Hospital

    Bergen, Vestland, 5009, Norway

  • Haukeland University Hospital

    Bergen, Vestland, 5021, Norway

Conditions

Explore the condition pages connected to this study.