New vaccine aims to stop rare but deadly brain infections from mosquitoes
NCT ID NCT06899802
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests a new vaccine called MVA-BN-WEV to prevent two types of equine encephalitis (Eastern and Venezuelan), which are rare but serious brain infections spread by mosquitoes. The study involves 411 healthy adults aged 18-50 and aims to find the best dose and dosing schedule. Researchers will measure immune responses and monitor safety over the trial period.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MVA-BN-WEV vaccine (a weakened virus vaccine designed to protect against two types of equine encephalitis)
What this could lead to
If successful, this could lead to a vaccine that protects people at high risk of exposure to Eastern and Venezuelan equine encephalitis, potentially preventing severe brain infections.
What could go wrong
This is a Phase 2 trial, so it is still early. The vaccine may not produce strong enough immunity, or side effects could be more common than expected. Success in this phase does not guarantee final approval.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Benchmark Research
Sacramento, California, 95864, United States
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Benchmark Research
Kenner, Louisiana, 70065, United States
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Benchmark Research
San Angelo, Texas, 76904, United States
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Clay-Platte Family Medicine, P.C./CCT Research
Kansas City, Missouri, 64151, United States
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Jefferson City Medical Group / Avacare
Jefferson City, Missouri, 65109, United States
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Johnson County Clin-Trials
Lenexa, Kansas, 66219, United States
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Lifeline Primary Care, Inc. / CCT Research
Lilburn, Georgia, 30047, United States
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Papillion Research Center/CCT Research
Papillion, Nebraska, 68046, United States
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Versailles Family Medicine, PLLC/CCT Research
Versailles, Kentucky, 40383, United States