Can muscle loss predict death in the ICU?

NCT ID NCT07280039

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 386 critically ill patients on breathing machines to see if losing 10% or more of thigh muscle within the first week in the hospital is linked to a higher chance of dying within 28 days. Researchers will use ultrasound to measure muscle size. The goal is to better understand how muscle wasting affects survival in intensive care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify high-risk ICU patients earlier and guide interventions to prevent muscle loss.
What could go wrong
This is an observational study, not a treatment trial. It only looks for a link, not a cause, and results may not apply to all ICU patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Critical Illness muscular atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University Hospital Brno

    Brno, Bohunice, 62500, Czechia

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Other studies related to the condition(s) this trial covers.