New hope for Tough-to-Treat myeloma: phase 3 trial launches

NCT ID NCT07258511

First seen Jan 11, 2026 · Last updated May 02, 2026 · Updated 21 times

Summary

This study tests a new drug, JNJ-79635322, against another targeted therapy for people with multiple myeloma that has come back or stopped responding after at least three prior treatments. About 400 adults will be randomly assigned to one of the two treatments to see which works better at shrinking tumors and delaying the disease from getting worse. The goal is to find a more effective option for patients who have run out of standard therapies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Assuta MC

    RECRUITING

    Tel Aviv, 69710, Israel

  • Baruch Padeh MC

    RECRUITING

    Ramat Poriya, 1520800, Israel

  • Bnai Zion Medical Center

    RECRUITING

    Haifa, 31048, Israel

  • Box Hill Hospital

    RECRUITING

    Box Hill, 3128, Australia

  • Carmel Medical Center

    RECRUITING

    Haifa, 34362, Israel

  • Chiba Cancer Center

    RECRUITING

    Chiba, 260 0801, Japan

  • Durham VAMC

    RECRUITING

    Durham, North Carolina, 27705, United States

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Fiona Stanley Hospital

    RECRUITING

    Murdoch, 6150, Australia

  • Florida Cancer Specialists & Research Institute

    RECRUITING

    Fort Myers, Florida, 33901, United States

  • Gold Coast University Hospital

    RECRUITING

    Southport, 4215, Australia

  • Hospital De Clinicas De Porto Alegre

    SUSPENDED

    Porto Alegre, 90035 903, Brazil

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Japanese Red Cross Medical Center

    RECRUITING

    Shibuya City, 150-8935, Japan

  • Kameda Medical Center

    RECRUITING

    Kamogawa, 296-8602, Japan

  • Kanagawa Cancer Center

    RECRUITING

    Yokohama, 241 8515, Japan

  • Mater Misericordiae Ltd

    RECRUITING

    Brisbane, 4101, Australia

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Mission Cancer Blood

    RECRUITING

    Waukee, Iowa, 50263, United States

  • Monash Medical Centre

    RECRUITING

    Clayton, 3168, Australia

  • Mount Sinai Brooklyn

    RECRUITING

    Brooklyn, New York, 11234, United States

  • Mount Sinai Chelsea

    RECRUITING

    New York, New York, 10011, United States

  • Norton Cancer Institute

    RECRUITING

    Louisville, Kentucky, 40207, United States

  • Oregon Health And Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Rambam Medical Center

    RECRUITING

    Haifa, 3109601, Israel

  • Shaare Zedek MC

    RECRUITING

    Jerusalem, 9103102, Israel

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, 52621, Israel

  • Shonan Kamakura General Hospital

    RECRUITING

    Kamakura-shi, 247-8533, Japan

  • Soroka Medical Center

    RECRUITING

    Beersheba, 8457108, Israel

  • St Vincents Hospital Melbourne

    RECRUITING

    Fitzroy, 3065, Australia

  • The Alfred Hospital

    RECRUITING

    Melbourne, 3004, Australia

  • The Jikei University Hospital

    RECRUITING

    Minato, 105-8471, Japan

  • Thomas Jefferson University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital

    RECRUITING

    Bunkyō City, 113 8677, Japan

  • USC Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

  • University of Connecticut Health Center

    RECRUITING

    Farmington, Connecticut, 06030, United States

  • University of Iowa Hospital and Clinics

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • Yale Cancer Center

    RECRUITING

    New Haven, Connecticut, 06510, United States

  • Yamanashi Prefectural Central Hospital

    RECRUITING

    Kofu, 400-0027, Japan

Conditions

Explore the condition pages connected to this study.