New drug combo aims to wipe out hidden myeloma after transplant

NCT ID NCT04876248

First seen Nov 10, 2025 · Last updated Jun 13, 2026 · Updated 26 times

Summary

This study tests whether a combination of belantamab mafodotin (a targeted chemotherapy) and lenalidomide can eliminate any remaining cancer cells in multiple myeloma patients who still have detectable disease after a stem cell transplant. The trial enrolls 4 adults with multiple myeloma who are not cancer-free after transplant. The goal is to see if this treatment can achieve a negative minimal residual disease status, meaning no cancer cells are found using sensitive tests.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

Conditions

Explore the condition pages connected to this study.