New drug cocktail aims to wipe out hidden myeloma cells after transplant

NCT ID NCT04876248

First seen Nov 10, 2025 · Last updated Apr 28, 2026 · Updated 22 times

Summary

This study tests whether a combination of belantamab mafodotin (a targeted chemotherapy) and lenalidomide can eliminate leftover cancer cells in multiple myeloma patients who still have signs of disease after a stem cell transplant. The goal is to achieve a state called minimal residual disease negativity, meaning no detectable cancer cells. The trial enrolls adults aged 18 and older with good performance status.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

Conditions

Explore the condition pages connected to this study.