New drug combo aims to fight blood cancer with fewer nerve problems

NCT ID NCT02441686

Summary

This study tested a combination of three cancer drugs (lenalidomide, bortezomib, and dexamethasone) in 46 adults newly diagnosed with multiple myeloma, a cancer of plasma cells. The main goals were to see how well the treatment worked to control the cancer and to check if giving one drug as an injection under the skin instead of into a vein would cause less nerve damage, a common and painful side effect. Researchers measured how many patients responded to treatment and tracked side effects over time.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Eastern Maine Medical Center

    Brewer, Maine, 04412, United States

  • Hematology Oncology of Northern New Jersey

    Morristown, New Jersey, 07962, United States

  • Massachusetts General Hosptial

    Boston, Massachusetts, 02114, United States

  • Virgina Piper Cancer Institute

    Minneapolis, Minnesota, 55407, United States

  • Virginia Piper Cancer Institute

    Coon Rapids, Minnesota, 55433, United States

Conditions

Explore the condition pages connected to this study.