New drug cocktail aims to keep multiple myeloma at bay longer after transplant

NCT ID NCT02659293

First seen Mar 08, 2026 · Last updated May 08, 2026 · Updated 6 times

Summary

This study tests whether adding two extra drugs (carfilzomib and dexamethasone) to standard lenalidomide maintenance therapy after a stem-cell transplant can delay the return of multiple myeloma. About 180 adults who have already had a transplant and are in stable condition will be randomly assigned to receive either the three-drug combo or lenalidomide alone. The main goal is to see if the combo extends the time before the disease worsens.

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Contacts and locations

Locations

  • Polish Myeloma Consortium

    Poznan, Poland

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • Wayne State University - Karmanos Cacner Institute

    Detroit, Michigan, 48201, United States

Conditions

Explore the condition pages connected to this study.