New drug cocktail aims to keep myeloma at bay after transplant

NCT ID NCT02659293

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding two more drugs (carfilzomib and dexamethasone) to the standard maintenance drug lenalidomide after a stem-cell transplant can keep multiple myeloma from coming back longer. About 180 adults who have already had a transplant and are in stable condition will be randomly assigned to one of the two treatment groups. The main goal is to see how long it takes for the cancer to worsen.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Polish Myeloma Consortium

    Poznan, Poland

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • Wayne State University - Karmanos Cacner Institute

    Detroit, Michigan, 48201, United States