Brain training and exercise combo shows promise for mild memory loss

NCT ID NCT05483790

Completed Symptom relief Sponsor: Huashan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested a multimodal program combining cognitive training, physical exercise, and healthy lifestyle education in 120 older adults (ages 50-75) with mild cognitive impairment or normal cognition. Participants were randomly assigned to the program or health education alone. The goal was to see if the program could improve memory and thinking, measured by tests and brain scans over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: multimodal behavioral intervention (cognitive training, physical exercise, healthy lifestyle education, and computerized interaction training)
What this could lead to: If it works, this could point toward a simple, non-drug program to help older adults maintain or improve memory and thinking skills.
What could go wrong: This is a small, completed study with 120 participants, so results may not apply to everyone. The intervention is complex and may be hard to replicate widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MILD COGNITIVE IMPAIRMENT THE COGNITIVE NORMAL ELDERLY

Contacts and locations

Locations

Huashan Hospital, Fudan University

Shanghai, Shanghai Municipality, 200030, China

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