Engineered immune cells take on stubborn lymphoma
NCT ID NCT04429438
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new approach using a mix of gene-modified immune cells (CAR-T cells) that target multiple proteins found on B cell lymphoma cells. The goal is to see if this combination is safe and can shrink tumors in patients whose cancer has not responded to standard treatments. The trial enrolls people aged 6 months and older with certain types of B cell lymphoma.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
gene-modified immune cells (CAR-T cells) targeting CD19 and other B cell markers
What this could lead to
If successful, this approach could offer a new treatment option for patients with B cell lymphoma that has not responded to standard therapies.
What could go wrong
This is an early-phase trial with a small number of participants, so results may not apply broadly. CAR-T therapy can cause serious side effects like cytokine release syndrome.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shenzhen Geno-Immune Medical Institute
RECRUITINGShenzhen, Guangdong, 518000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••