New TB vaccine candidate MTBVAC enters Mid-Stage human trial

NCT ID NCT06997367

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tests a new tuberculosis vaccine called MTBVAC (BBV169) in 164 healthy adolescents and adults. Some participants get the new vaccine, others get the standard BCG vaccine. The study checks how safe the vaccine is and how well it triggers an immune response, aiming to find a better TB vaccine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MTBVAC (BBV169) vaccine

What this could lead to

If successful, this could lead to a more effective tuberculosis vaccine than the current BCG, potentially reducing TB cases worldwide.

What could go wrong

This is a mid-stage trial with only 164 participants, so results may not apply broadly. The vaccine is still experimental and may not prove safer or more effective than BCG.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tuberculosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AIIMS-Delhi

    New Delhi, 110029, India

  • Guru Teg Bahadur Hospital

    Delhi, 11009, India