Stem cell infusion aims to buy time for kids with fatal brain disease
NCT ID NCT06030648
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests whether a single infusion of donated mesenchymal stem cells is safe for children with cerebral adrenoleukodystrophy (cALD), a rare and life-threatening brain disease. The stem cells are given as a temporary bridge to buy time before a more definitive treatment like a bone marrow transplant or gene therapy. Only 10 participants are being enrolled, and the main goal is to check for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mesenchymal stem cells (MSC)
What this could lead to
If it works, this could provide a safe way to stabilize brain inflammation in children with cerebral adrenoleukodystrophy while they wait for a stem cell transplant or gene therapy.
What could go wrong
This is a very early Phase 1 trial with only 10 participants, so it is primarily checking safety, not effectiveness. The study is currently suspended, and the treatment is only a temporary bridge, not a cure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Masonic Cancer Center, University of Minnesota
Minneapolis, Minnesota, 55455, United States