Stem cell shot aims to cure radiation dry mouth
NCT ID NCT04489732
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested whether injecting a patient's own stem cells into the saliva gland could safely help dry mouth caused by radiation therapy for head and neck cancer. Six participants received one injection, with a second offered later. The main goal was to check for side effects like pain or serious complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mesenchymal stromal cells (stem cells from the patient's own bone marrow)
What this could lead to
If it works, this could point toward a treatment for chronic dry mouth after radiation therapy.
What could go wrong
This is a very early, small pilot study with only 6 participants, so results may not apply widely. The main risk is pain or serious side effects from the injection.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Wisconsin
Madison, Wisconsin, 53705, United States