Cord blood stem cells take on lupus in new trial
NCT ID NCT02633163
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a single infusion of stem cells from donated umbilical cords could help adults with lupus that does not respond to standard treatments. 81 participants received either a low dose, high dose, or placebo infusion, while continuing their usual medications. The goal was to see if the stem cell group had better disease control at 24 weeks, measured by a standard lupus activity score.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
umbilical cord mesenchymal stem cells (MSCs)
What this could lead to
If this works, it could point toward a new treatment option for people with lupus that is not controlled by current therapies.
What could go wrong
This is a phase II trial with only 81 participants, so results may not apply to everyone. Stem cell treatments can have side effects like infusion reactions or infection, and the benefit over standard care is not yet proven.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
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Emory University
Atlanta, Georgia, 30322, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Oklahoma Medical Research Foundation
Oklahoma City, Oklahoma, 73104, United States
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The Feinstein Institute for Medical Research
Manhasset, New York, 11030, United States
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University of California - San Diego
San Diego, California, 92093, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Rochester Medical Center
Rochester, New York, 14642, United States