Common drugs tested to reverse MS disability

This trial tested whether a combination of two existing, safe drugs—metformin (for diabetes) and clemastine (an antihistamine)—could help repair the protective coating around nerves in people with relapsing multiple sclerosis (MS). The goal was to see if this repair process, called remyelination, could protect nerves and potentially slow or reverse disability. The 70 participants, aged 25-50, took the drug combination or a placebo for 24 weeks while continuing their standard MS treatments.