New mRNA vaccine aims to tame genital herpes Flare-Ups

NCT ID NCT06033261

First seen May 12, 2026 · Last updated May 15, 2026 · Updated 2 times

Summary

This study tested a new mRNA vaccine (mRNA-1608) in 303 adults aged 18-55 with recurrent genital herpes caused by HSV-2. The goal was to see if the vaccine is safe and can reduce the number of outbreaks. Participants received either the vaccine or a placebo, and researchers tracked side effects and recurrence episodes for 6 months after the second dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Accel Clinical Sites Network - Cahaba Medical Care

    Birmingham, Alabama, 35218, United States

  • Acclaim Clinical Research

    San Diego, California, 92120, United States

  • Alliance for Multispecialty Research, LLC

    Newton, Kansas, 67114, United States

  • Cedars-Sinai Medical Center/Carbon Health

    Beverly Hills, California, 90211, United States

  • DM Clinical Research

    Southfield, Michigan, 48076, United States

  • DM Clinical Research

    Houston, Texas, 77081, United States

  • DM Clinical Research

    Tomball, Texas, 77064, United States

  • Fenway Health

    Boston, Massachusetts, 02215, United States

  • Health Research of Hampton Roads

    Newport News, Virginia, 23606, United States

  • Helios CR, Inc Fort Worth

    Fort Worth, Texas, 76107, United States

  • Johnson County Clin-Trials (JCCT)

    Lenexa, Kansas, 66219, United States

  • M3 Wake Research, Inc.

    Raleigh, North Carolina, 27612, United States

  • Multi-Specialty Research Associates, Inc.

    Lake City, Florida, 32055, United States

  • Noble Clinical Research

    Tucson, Arizona, 85704, United States

  • Research Works

    New Orleans, Louisiana, 70125, United States

  • Rochester Clinical Research

    Rochester, New York, 14609, United States

  • Sun Research Institute

    San Antonio, Texas, 78215, United States

  • Suncoast Research Associates, LLC

    Miami, Florida, 33173, United States

  • University of Washington Virology Research Clinic

    Seattle, Washington, 98104, United States

  • Velocity Clinical Research

    Grand Island, Nebraska, 68803, United States

  • Velocity Clinical Research

    Norfolk, Nebraska, 68701, United States

  • Velocity Clinical Research Cleveland

    Beachwood, Ohio, 44122, United States

  • Velocity Clinical Research, Austin

    Cedar Park, Texas, 78613, United States

Conditions

Explore the condition pages connected to this study.