New mRNA vaccine aims to tame genital herpes recurrences
NCT ID NCT06033261
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested an experimental mRNA vaccine (mRNA-1608) in 303 healthy adults aged 18 to 55 with recurrent genital herpes caused by HSV-2. The goal was to see if the vaccine is safe and can reduce the number of outbreaks. Participants received different doses of the vaccine or a placebo, and researchers tracked side effects and recurrence episodes over six months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Accel Clinical Sites Network - Cahaba Medical Care
Birmingham, Alabama, 35218, United States
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Acclaim Clinical Research
San Diego, California, 92120, United States
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Alliance for Multispecialty Research, LLC
Newton, Kansas, 67114, United States
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Cedars-Sinai Medical Center/Carbon Health
Beverly Hills, California, 90211, United States
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DM Clinical Research
Southfield, Michigan, 48076, United States
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DM Clinical Research
Houston, Texas, 77081, United States
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DM Clinical Research
Tomball, Texas, 77064, United States
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Fenway Health
Boston, Massachusetts, 02215, United States
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Health Research of Hampton Roads
Newport News, Virginia, 23606, United States
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Helios CR, Inc Fort Worth
Fort Worth, Texas, 76107, United States
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Johnson County Clin-Trials (JCCT)
Lenexa, Kansas, 66219, United States
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M3 Wake Research, Inc.
Raleigh, North Carolina, 27612, United States
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Multi-Specialty Research Associates, Inc.
Lake City, Florida, 32055, United States
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Noble Clinical Research
Tucson, Arizona, 85704, United States
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Research Works
New Orleans, Louisiana, 70125, United States
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Rochester Clinical Research
Rochester, New York, 14609, United States
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Sun Research Institute
San Antonio, Texas, 78215, United States
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Suncoast Research Associates, LLC
Miami, Florida, 33173, United States
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University of Washington Virology Research Clinic
Seattle, Washington, 98104, United States
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Velocity Clinical Research
Grand Island, Nebraska, 68803, United States
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Velocity Clinical Research
Norfolk, Nebraska, 68701, United States
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Velocity Clinical Research Cleveland
Beachwood, Ohio, 44122, United States
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Velocity Clinical Research, Austin
Cedar Park, Texas, 78613, United States
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