New MRI technique may spot aggressive rectal cancers before surgery

NCT ID NCT07269912

Not yet recruiting Diagnosis Sponsor: Sichuan Cancer Hospital and Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether a special type of MRI, called IVIM-MRI, can predict lymphovascular invasion (LVI) in rectal cancer patients before surgery. LVI is a sign that the cancer may spread, and knowing this ahead of time could help doctors choose the best treatment. The study plans to enroll 400 participants and will follow them for two years to see if the MRI predictions match actual outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: intravoxel incoherent motion magnetic resonance imaging (IVIM-MRI)
What this could lead to: If successful, this could provide a non-invasive way to predict which rectal cancers are more likely to spread, allowing doctors to tailor treatments more precisely.
What could go wrong: This is an early-stage study with 400 participants, and previous similar MRI methods have shown limited accuracy. The technique may not be reliable enough for routine use.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROGNOSIS RECTAL NEOPLASMS

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