New MRI technique may spot aggressive rectal cancers before surgery

NCT ID NCT07269912

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether a special type of MRI, called IVIM-MRI, can predict lymphovascular invasion (LVI) in rectal cancer patients before surgery. LVI is a sign that the cancer may spread, and knowing this ahead of time could help doctors choose the best treatment. The study plans to enroll 400 participants and will follow them for two years to see if the MRI predictions match actual outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

intravoxel incoherent motion magnetic resonance imaging (IVIM-MRI)

What this could lead to

If successful, this could provide a non-invasive way to predict which rectal cancers are more likely to spread, allowing doctors to tailor treatments more precisely.

What could go wrong

This is an early-stage study with 400 participants, and previous similar MRI methods have shown limited accuracy. The technique may not be reliable enough for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.