Can yearly MRIs catch second cancers in retinoblastoma survivors?

NCT ID NCT03026998

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether yearly MRI scans can find new head and neck or brain cancers early in people who had hereditary retinoblastoma and were treated with radiation. Researchers will follow 88 participants for 10 years to see if early detection leads to better surgery outcomes. The goal is to improve survival and preserve vision.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that regular MRI screening helps catch new cancers early, leading to better treatment and survival for people with hereditary retinoblastoma.

What could go wrong

This is an observational study, not a treatment trial. It may not prove that screening improves outcomes, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hereditary retinoblastoma retinoblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institut Curie

    Paris, 75005, France