New drug shows promise for Hard-to-Treat throat cancer
NCT ID NCT05126719
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called MRG003 in adults whose nasopharyngeal cancer has come back or spread and hasn't responded to standard treatments. The goal is to see if the drug can shrink tumors and how safe it is. About 238 participants will receive the drug, and researchers will track tumor response and side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cancer Hospital of Shantou University Medical College
Shantou, Guangdong, 515041, China
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Chongqing University Cancer Hospital
Chongqing, Chongqing Municipality, 400030, China
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First Affiliated Hospital of Gannan Medical University
Ganzhou, Jiangxi, 341001, China
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Fujian Cancer Hospital
Fuzhou, Fujian, 350014, China
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Ganzhou Cancer Hospital
Ganzhou, Jiangxi, 341005, China
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Guangxi Medical University Affiliated Tumor Hospital
Nanning, Guangxi, 530021, China
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Guigang City People's Hospital
Guigang, Guangxi, 537199, China
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Hainan General Hospital
Haikou, Hainan, 570311, China
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Henan Cancer Hospital
Zhengzhou, Henan, 450003, China
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Hunan Cancer Hospital
Changsha, Hunan, 410031, China
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Jiangxi Cancer Hospital
Nanchang, Jiangxi, 330029, China
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Maoming People's Hospital
Maoming, Guangdong, 525000, China
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Peking University Cancer Hospital
Beijing, Beijing Municipality, 100142, China
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People's Hospital of Guangxi Zhuang Autonomous Region
Nanning, Guangxi, 530021, China
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Shanghai East Hospital
Shanghai, Shanghai Municipality, 200123, China
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Sichuan Cancer Hospital
Chengdu, Sichuan, 610041, China
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Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, 510000, China
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The Affiliated Cancer Hospital of Guizhou Medical University
Guiyang, Guizhou, 550000, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430022, China
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Yibin Second People's Hospital
Yibin, Sichuan, 644000, China
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Yue Bei People's Hospital
Shaoguan, Guangdong, 512026, China
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Zhejiang Cancer Hospital
Hangzhou, Zhejiang, 310022, China
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Zhongshan City People's Hospital
Zhongshan, Guangdong, 528403, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New drug combo targets Hard-to-Treat nasopharyngeal cancer
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- New cocktail of drugs shows promise for Hard-to-Treat throat cancer
- New drug cocktail aims to outdo chemo for tough throat cancer
- New hope for advanced nose and throat cancer with combo therapy