MRI-Guided radiation: a sharper weapon against cancer?

NCT ID NCT04135794

Ongoing Knowledge-focused Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing a new radiation technique that uses real-time MRI scans to target cancer more precisely. About 377 adult cancer patients will receive this treatment and have extra scans and quality-of-life surveys. The goal is to see if this approach improves tumor control and reduces side effects compared to standard radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Magnetic Resonance-guided adaptive radiotherapy (MRgART) using an integrated magnetic resonance linear accelerator (MRL)
What this could lead to: If successful, this could lead to more precise cancer radiation treatments that better target tumors while sparing healthy tissue, potentially improving outcomes and reducing side effects.
What could go wrong: This is an observational study still gathering data, so it is too early to know if the approach truly improves outcomes. The results may not apply to all cancer types or stages.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER

Contacts and locations

Locations

Princess Margaret Cancer Centre

Toronto, Ontario, M5G 2M9, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.