Brain-Scan AI could spot Parkinson's without costly PET imaging

NCT ID NCT04334902

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested a software called mPDia that uses MRI brain scans to help doctors diagnose neurodegenerative parkinsonism, a group of movement disorders including Parkinson's disease. The study involved 221 adults and compared mPDia's accuracy to standard PET scans. The goal was to see if this AI tool could provide a simpler, more widely available diagnostic option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mPDia clinical decision support software (device)
What this could lead to
If successful, mPDia could offer a faster, more accessible way to diagnose parkinsonism using standard MRI instead of expensive PET scans.
What could go wrong
This is a retrospective study, not a prospective trial, so real-world performance may differ. The software's accuracy depends on MRI quality and may not replace PET scans in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, South Korea

  • Catholic University of Korea, Seoul ST. Mary's Hospital

    Seoul, South Korea

  • Cha Medical Center

    Gyeonggi-do, South Korea

  • Gachon University Gil Medical Center

    Incheon, South Korea

  • Gangnam Severance Hospital

    Seoul, South Korea

  • Hallym University Dongtan Sacred Heart Hospital

    Gyeonggi-do, South Korea

  • Hallym University Sacred Heart Hospital

    Gyeonggi-do, South Korea

  • Korea University Ansan Hospital

    Gyeonggi-do, South Korea

  • Korea University Guro Hospital

    Seoul, South Korea

  • KyungHee University Medical Center

    Seoul, South Korea

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