New drug may boost stem cell harvest for sickle cell gene therapy
NCT ID NCT06442761
First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 32 times
Summary
This early-stage study tests whether the drug motixafortide is safe for people with sickle cell disease and whether it can increase the number of stem cells that can be collected from their blood. These stem cells could be used in future gene therapies or transplants. The study involves 15 adults with severe sickle cell disease and aims to find the best dosing plan for larger studies.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Heart, Blood and Lung Institute-Cellular and Molecular Therapy Branch
RECRUITINGBethesda, Maryland, 20814, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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