Could a tiny dose of morphine make C-Section recovery less painful?

NCT ID NCT06797973

Recruiting now Symptom relief Sponsor: Anne Juul Wikkelsø Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether adding a small amount of morphine to the standard spinal anesthesia can improve pain control after a planned C-section, without causing serious side effects for mothers or babies. About 1,300 women will be randomly assigned to receive either morphine or a placebo (salt water) in their spinal injection. All participants will also get standard painkillers after surgery. Researchers will track pain levels, side effects, and any serious complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: morphine
What this could lead to: If it works, this could provide a simple way to reduce pain after C-section without needing extra strong painkillers.
What could go wrong: This is a phase 4 trial, so the drug is already approved, but the low dose may not work well enough, or side effects like nausea or breathing problems could outweigh benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CAESAREAN SECTION POSTOPERATIVE PAIN

Contacts and locations

Locations

Aarhus University Hospital
RECRUITING

Aarhus, 8200, Denmark
Copenhagen University Hospital - Amager and Hvidovre, Hvidovre
RECRUITING

Hvidovre, 2650, Denmark
Copenhagen University Hospital - Herlev and Gentofte, Herlev
NOT_YET_RECRUITING

Herlev, 2730, Denmark
Copenhagen University Hospital - North Zealand, Hillerød
NOT_YET_RECRUITING

Hillerød, 3400, Denmark
Copenhagen University Hospital - Rigshospitalet
NOT_YET_RECRUITING

Copenhagen, 2100, Denmark
University Hospital of Southern Denmark - Lillebælt Hospital, Kolding
RECRUITING

Kolding, 6000, Denmark
University Hospital of Southern Denmark - Odense University Hospital
RECRUITING

Odense C, 5000, Denmark
Zealand University Hospital
RECRUITING

Roskilde, 4000, Denmark

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