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New hope for lymphoma patients: drug duo may beat standard chemo

NCT ID NCT06284122

Recruiting now Disease control Sponsor: The Lymphoma Academic Research Organisation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new combination of two drugs (mosunetuzumab and lenalidomide) against standard chemotherapy for people with untreated follicular lymphoma. About 790 participants will be randomly assigned to one of the two treatments. The goal is to see if the new combo keeps the cancer from growing longer than standard therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FOLLICULAR LYMPHOMA

Contacts and locations

Locations

  • AGAPLESION DIAKONIEKLINIKUM ROTENBURG - Klinik für Hämatologie, Onkologie und Nephrologie

    TERMINATED

    Rotenburg (Wümme), 27356, Germany

  • AZ SINT-JAN BRUGGE - OOSTENDE AV - Service Hématologie

    RECRUITING

    Bruges, 8000, Belgium

  • BRUEDERKRANKENHAUS ST. JOSEF PADERBORN - Klinik für Hämatologie und Onkologie

    RECRUITING

    Paderborn, 33098, Germany

  • CENTRE HENRI BECQUEREL - Service Hématologie

    RECRUITING

    Rouen, 76038, France

  • CENTRE HOSPITALIER DE NIORT - Médecine interne

    RECRUITING

    Niort, 79021, France

  • CENTRE HOSPITALIER JEAN ROUGIER - Service d'Oncologie - Hématologie

    RECRUITING

    Cahors, 46005, France

  • CH ANNECY GENEVOIS - SITE D'ANNECY - Service Hématologie

    RECRUITING

    Pringy, 74374, France

  • CH DE BRETAGNE ATLANTIQUE - HOPITAL CHUBERT - Service Hématologie

    RECRUITING

    Vannes, 56017, France

  • CH DE LA COTE BASQUE - Service Hématologie

    RECRUITING

    Bayonne, 64100, France

  • CH DE VALENCIENNES - HOPITAL JEAN BERNARD - Service Hématologie

    RECRUITING

    Valenciennes, 59322, France

  • CH METROPOLE SAVOIE - SITE CHAMBERY - Service Hématologie

    RECRUITING

    Chambéry, 73011, France

  • CH d'AVIGNON - HOPITAL HENRI DUFFAUT - Service d'Onco-Hématologie

    RECRUITING

    Avignon, 84000, France

  • CHARITE UNIVERSITATSMEDIZIN BERLIN - Med. Klinik m. S. Hämatologie, Onkologie, Tumorimmunologie

    RECRUITING

    Berlin, 13353, Germany

  • CHD DE VENDEE - Service Hématologie

    RECRUITING

    La Roche-sur-Yon, 85925, France

  • CHI POISSY SAINT-GERMAIN-EN-LAYE - Service Hématologie

    RECRUITING

    Poissy, 78303, France

  • CHRU DE LILLE - HOPITAL CLAUDE HURIEZ - Service Hématologie

    RECRUITING

    Lille, 59037, France

  • CHU BRABOIS - Service Hématologie

    RECRUITING

    Vandœuvre-lès-Nancy, 54511, France

  • CHU BRETONNEAU - Service Cancérologie - Hématologie et Thérapie Cellulaire

    RECRUITING

    Tours, 37044, France

  • CHU DE BORDEAUX - HOPITAL HAUT-LEVEQUE - CENTRE FRANCOIS MAGENDIE - Service d'Hématologie et Thérapie Cellulaire

    RECRUITING

    Pessac, 33604, France

  • CHU DE GRENOBLE - Service Hématologie

    RECRUITING

    La Tronche, 38700, France

  • CHU DE LIEGE - Service Hématologie

    RECRUITING

    Liège, 4000, Belgium

  • CHU DE LIMOGES - HOPITAL DUPUYTREN - Service Hématologie Clinique et Thérapie Cellulaire

    RECRUITING

    Limoges, 87042, France

  • CHU DE MONTPELLIER - Département d'Hématologie Clinique

    RECRUITING

    Montpellier, 34090, France

  • CHU DE NANTES - Service Hématologie

    RECRUITING

    Nantes, 44093, France

  • CHU DE POITIERS - HOPITAL DE LA MILETRIE - Service d'Oncologie Hématologique et Thérapie Cellulaire

    RECRUITING

    Poitiers, 86021, France

  • CHU DE REIMS - HOPITAL ROBERT DEBRE - Service Hématologie

    RECRUITING

    Reims, 57092, France

  • CHU DIJON BOURGOGNE - Service Hématologie Clinique

    RECRUITING

    Dijon, 21000, France

  • CHU ESTAING - Service Thérapie Cellulaire et Hématologie Clinique

    RECRUITING

    Clermont-Ferrand, 63003, France

  • CHU JEAN MINJOZ - Service Hématologie

    RECRUITING

    Besançon, 25030, France

  • CHU LYON-SUD - Hématologie

    RECRUITING

    Pierre-Bénite, 69495, France

  • CHU PONTCHAILLOU - Hématologie Clinique

    RECRUITING

    Rennes, 35033, France

  • CHU UCL NAMUR - SITE GODINNE - Service Hématologie

    RECRUITING

    Yvoir, 5530, Belgium

  • GEMEINSCHAFTSKLINIKUM MITTELRHEIN GGMBH - Innere Medizin - Hämatologie/Onkologie

    RECRUITING

    Koblenz, 56073, Germany

  • GEORG-AUGUST-UNIV, GOETTINGEN - Klinik fur Haematologie und Medizinisched Onkologie

    RECRUITING

    Göttingen, 37075, Germany

  • GESUNDHEITSZENTRUM ST. MARIEN GMBH - Hämatologie/Onkologie

    RECRUITING

    Amberg, 92224, Germany

  • GH REGION MULHOUSE ET SUD ALSACE - HOPITAL EMILE MULLER - Service Hématologie

    RECRUITING

    Mulhouse, 68100, France

  • GOETHE UNIVERSITÄT FRANKFURT - Medizinische Klinik II Onkologie

    RECRUITING

    Frankfurt, Germany

  • GRAND HOPITAL DE CHARLEROI - Service Hématologie

    RECRUITING

    Charleroi, 6000, Belgium

  • GUSTAVE ROUSSY CANCER CAMPUS GRAND PARIS - Département Médecine Oncologique

    RECRUITING

    Villejuif, 94085, France

  • Gemeinschaftspraxis Fur Hamatologie Und Onkologie

    RECRUITING

    Münster, 48149, Germany

  • HELIOS UNIVERSITÄTSKLINIKUM WUPPERTAL - Hämatologie und Onkologie

    RECRUITING

    Wuppertal, 42283, Germany

  • HELORA - Hôpital de La Louvière - Site Jolimont - Service Hématologie Clinique

    RECRUITING

    La Louvière, 7100, Belgium

  • HFR Fribourg - Hématologie

    RECRUITING

    Villars-sur-Glâne, 1752, Switzerland

  • HOPITAL HENRI MONDOR - Unité Hémopathies Lymphoïdes

    RECRUITING

    Créteil, 94010, France

  • HOPITAL SAINT VINCENT-DE-PAUL - Service Hématologie

    RECRUITING

    Lille, 59020, France

  • HOPITAL SAINT-LOUIS - Service Hématologie

    RECRUITING

    Paris, 75475, France

  • HOSPITAL 12 DE OCTUBRE - Servicio de Hematología y Hemoterapia

    RECRUITING

    Madrid, 28041, Spain

  • HOSPITAL CENTRAL ASTURIAS - Servicio de Hematología

    RECRUITING

    Oviedo, 33011, Spain

  • HOSPITAL CLINIC BARCELONA - Hematology department

    RECRUITING

    Barcelona, 8036, Spain

  • HOSPITAL CLINICO DE VALENCIA - Servicio de Hematologia

    RECRUITING

    Valencia, 46010, Spain

  • HOSPITAL CLINICO SALAMANCA - Servicio de Hematologia

    RECRUITING

    Salamanca, 37007, Spain

  • HOSPITAL COSTA DEL SOL MARBELLA - Servicio de hematologia

    RECRUITING

    Marbella, 29603, Spain

  • HOSPITAL DE LA SANTA CREU I SANT PAU - Servicio de Hematología

    RECRUITING

    Barcelona, 8025, Spain

  • HOSPITAL DURAN I REYNALS - ICO Oncologia

    RECRUITING

    Barcelona, 08908, Spain

  • HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARANON - Servicio de Hematología-UTMO

    RECRUITING

    Madrid, 28007, Spain

  • HOSPITAL PUERTA DEL HIERRO - Servicio Hematologia

    RECRUITING

    Madrid, 28222, Spain

  • HOSPITAL UNIVERSITARIO ARNAU DE VILANOVA - Servicio Hematologia

    RECRUITING

    Lleida, 25198, Spain

  • HOSPITAL UNIVERSITARIO DE ALBACETE-Servicio de Hematologia

    RECRUITING

    Albacete, 02006, Spain

  • HOSPITAL UNIVERSITARIO DE LA PRINCESA - Hematología

    RECRUITING

    Madrid, 28006, Spain

  • HOSPITAL UNIVERSITARIO DR. NEGRIN-Servicio de Hematologia

    RECRUITING

    Las Palmas de Gran Canaria, 35010, Spain

  • HOSPITAL UNIVERSITARIO FUNDACION ALCORCON - Consulta de Hematología Hospital de Día Médico

    RECRUITING

    Madrid, 28922, Spain

  • HOSPITAL VALL D'HEBRON - Hematology Service

    RECRUITING

    Barcelona, 8035, Spain

  • Helios Klinikum Berlin-Buch - Klinik für Hämatologie und Stammzelltransplantation

    RECRUITING

    Berlin, 13125, Germany

  • Hôpitaux Universitaires de Genève (HUG) - Hématologie

    RECRUITING

    Geneva, 1205, Switzerland

  • INSTITUT BERGONIE - Service d'Oncologie Médicale

    RECRUITING

    Bordeaux, 33076, France

  • INSTITUT CURIE - SITE SAINT-CLOUD - Service Hématologie

    RECRUITING

    Saint-Cloud, 92210, France

  • INSTITUT DE CANCEROLOGIE STRASBOURG EUROPE - Unité de Recherche Clinique

    RECRUITING

    Strasbourg, 67033, France

  • INSTITUT JULES BORDET - Service Hématologie

    RECRUITING

    Brussels, 1070, Belgium

  • INSTITUT PAOLI CALMETTES - Service Hématologie

    RECRUITING

    Marseille, 13273, France

  • INSTITUTO PORTUGUES DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL - Departamento Hematologia

    RECRUITING

    Lisbon, 1099, Portugal

  • IUCT ONCOPOLE - Service Hématologie

    RECRUITING

    Toulouse, 31059, France

  • Institut de Cancérologie et d'Hématologie Universitaire de Saint-Étienne - Service Hématologie

    RECRUITING

    Saint-Priest-en-Jarez, 42270, France

  • KLINIKEN MARIA HILF GMBH KRANKENHAUS ST. FRANZISK - Hämatologie, Onkologie & Gastroenterologie

    RECRUITING

    Mönchengladbach, 41063, Germany

  • KLINIKUM AM STEINENBERG REUTLINGEN GMBH - Medizinische Klinik I

    RECRUITING

    Reutlingen, 72764, Germany

  • KLINIKUM BREMEN-MITTE - Gesundheit Nord gGmbH - Hämatologisch-Onkologische Tagesklinik

    RECRUITING

    Bremen, 28205, Germany

  • KLINIKUM CHEMNITZ GGMBH - Klinik f. Innere Medizin III

    RECRUITING

    Chemnitz, 9116, Germany

  • KLINIKUM GROSSHADERN DER LMU MUNCHEN - Hämatologie und Onkologie allgemein

    RECRUITING

    München, 81377, Germany

  • KLINIKUM RECHTS DER ISAR, III MED KLINIK DER TU - Hämatologie und Onkologie

    RECRUITING

    München, 81675, Germany

  • KLINIKUM REGION HANNOVER GMBH KLINIK FÜR HÄMATOLOGIE-Onkologie und immunologie

    RECRUITING

    Hanover, 30459, Germany

  • Kantonsspital Baselland - Zentrum Onkologie & Hämatologie

    WITHDRAWN

    Liestal, 4410, Switzerland

  • Kantonsspital Graubunden - Departement Innere Medizin Medizinische Onkologie und Hämatologie

    RECRUITING

    Chur, 7000, Switzerland

  • Kantonsspital Olten - Hämatologie

    NOT_YET_RECRUITING

    Olten, 4600, Switzerland

  • Kepler Universitaetsklinikum - Univ.-Klinik für Hämatologie und Internistische Onkologie

    RECRUITING

    Linz, 4021, Austria

  • Klinikum Wels-Grieskirchen GMBH - IVth Internal Department

    RECRUITING

    Wels, 4600, Austria

  • Krankenhaus der Barmherzigen Brüder Graz - Abteilung Für Innere Medizin I

    RECRUITING

    Graz, 8020, Austria

  • Krems University Hospital - Abteilung Für Innere Medizin 2

    RECRUITING

    Krems, 3500, Austria

  • LAKUMED KLINIKUM - Onkologisches und palliativmedizinisches Netzwerk Landshut

    RECRUITING

    Landshut, 84036, Germany

  • LKH HOCHSTEIERMARK - Department für Hämato-Onkologie

    RECRUITING

    Leoben, 8700, Austria

  • MEDICAL CENTER - UNIVERSITY OF FREIBURG - Klinik für Innere Medizin I Hämatologie, Onkologie und Stammzelltransplantation

    RECRUITING

    Freiburg im Breisgau, 79106, Germany

  • MVZ FÜR HÄMATOLOGIE UND ONKOLOGIE RAVENSBURG GMBH - Hematology

    RECRUITING

    Ravensburg, 86212, Germany

  • Medical University of Vienna - Department of Hematology and Hemostaseology

    RECRUITING

    Vienna, 1090, Austria

  • ONKOLOGIE LERCHENFELD - OncoResearch Lerchenfeld GmbH

    WITHDRAWN

    Hamburg, 22081, Germany

  • Oncology Institute of Southern Switzerland (IOSI) - Department of Oncology

    RECRUITING

    Bellinzona, 6500, Switzerland

  • Paracelsus Medical University - 3rd Medical Department

    RECRUITING

    Salzburg, 5020, Austria

  • SOZIALSTIFTUNG BAMBERG - KLINIKUM AM BRUDERWALD - Hämatologie und internistische Onkologie

    RECRUITING

    Bamberg, 96049, Germany

  • Spital STS AG - Onkologie und Hämatologiezentrum

    RECRUITING

    Thun, 3600, Switzerland

  • Stadtspital Zürich Triemli - Medizinische Onkologie und Hämatologie

    WITHDRAWN

    Zurich, 8063, Switzerland

  • UKSH UNIVERSITAETSKLINIKUM SCHLESWIG-HOLSTEIN - Med. Klinik II - Hämatologie und Onkologie

    RECRUITING

    Kiel, 24105, Germany

  • UNIV KLINIKUM ULM - INNERE MEDIZIN III - Service Hématologie

    RECRUITING

    Ulm, 89081, Germany

  • UNIVERSITAETSKLINIKUM ESSEN - Klinik f. Hämatologie

    WITHDRAWN

    Essen, 45147, Germany

  • UNIVERSITAIR ZIEKENHUIS GENT - Service Hématologie

    RECRUITING

    Ghent, 9000, Belgium

  • UNIVERSITATSKLINIKUM HALLE (SAALE) - Klinik für Innere Medizin IV

    RECRUITING

    Halle, 6097, Germany

  • UNIVERSITATSKLINIKUM LUBECK - Klinik für Hämatologie und Onkologie

    RECRUITING

    Lübeck, 23538, Germany

  • UNIVERSITATSKLINIKUM REGENSBURG - Klinik für Innere Medizin III

    RECRUITING

    Regensburg, 93053, Germany

  • UNIVERSITE CATHOLIQUE DE LOUVAIN SAINT-LUC - Service Hématologie

    RECRUITING

    Brussels, 1200, Belgium

  • UNIVERSITY WURZBURG - Hämatologie

    RECRUITING

    Würzburg, 97080, Germany

  • UNIVERSITÄT ROSTOCK - Hämatologie/Onkologie

    RECRUITING

    Rostock, 18057, Germany

  • UNIVERSITÄTSKLINIK DÜSSELDORF-Klinik für Hämatologie, Onkologie und Klinische Immunologie

    RECRUITING

    Düsseldorf, 40225, Germany

  • UNIVERSITÄTSKLINIKUM HEIDELBERG - Innere Medizin V

    RECRUITING

    Heidelberg, 69120, Germany

  • UNIVERSITÄTSKLINIKUM JENA-Klinik für Innere Medizin II

    RECRUITING

    Jena, 07747, Germany

  • Univ. Klinikum ST.PÖLTEN - Klinische Abteilung Für Innere Medizin 1

    RECRUITING

    Sankt Pölten, 3100, Austria

  • Universitätsklinikum Wiener Neustadt - Klinische Abteilung für Innere Medizin III

    WITHDRAWN

    Wiener Neustadt, 2700, Austria

  • Universitätsklinikum des Saarlandes - Klinik für Innere Medizin I - Onkologie, Hämatol. Immun. & Rheumatololgie

    RECRUITING

    Homburg, 66421, Germany

  • Universtatsklinikum Munster

    RECRUITING

    Münster, 48149, Germany

  • VIVANTES KLINIKUM AM URBAN - Hämatologie und Onkologie

    RECRUITING

    Berlin, 10967, Germany

  • WESTPFALZ KLINIKUM - Klinik für Innere Medizin I

    RECRUITING

    Kaiserslautern, 67655, Germany

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