New drug cocktail aims to free myelofibrosis patients from frequent blood transfusions
NCT ID NCT06517875
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 22 times
Summary
This study tests whether combining two drugs, momelotinib and luspatercept, can help people with myelofibrosis go without blood transfusions for at least 12 weeks. About 68 adults who either haven't tried or have already used certain other treatments will take part. The goal is to manage the disease and reduce the need for transfusions, not to cure it.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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GSK Investigational Site
RECRUITINGAnn Arbor, Michigan, 48109, United States
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RECRUITINGNew York, New York, 10032, United States
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GSK Investigational Site
RECRUITINGNashville, Tennessee, 37203, United States
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GSK Investigational Site
RECRUITINGHouston, Texas, 77030, United States
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RECRUITINGSeattle, Washington, 98109, United States
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GSK Investigational Site
RECRUITINGVancouver, British Columbia, V6Z 1Y6, Canada
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GSK Investigational Site
RECRUITINGToronto, Ontario, M5G 2M9, Canada
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GSK Investigational Site
RECRUITINGMontreal, Quebec, H3T 1E2, Canada
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RECRUITINGMontreal, Quebec, H4A 3J1, Canada
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GSK Investigational Site
RECRUITINGAngers, 49933, France
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GSK Investigational Site
RECRUITINGBrest, 29609, France
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GSK Investigational Site
RECRUITINGLyon, 69004, France
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GSK Investigational Site
RECRUITINGNice, 06202, France
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GSK Investigational Site
RECRUITINGNîmes, 30029, France
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GSK Investigational Site
RECRUITINGParis, 75010, France
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GSK Investigational Site
RECRUITINGPoitiers, 86021, France
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GSK Investigational Site
RECRUITINGEssen, 45147, Germany
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GSK Investigational Site
RECRUITINGJena, 07747, Germany
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GSK Investigational Site
RECRUITINGLübeck, 23538, Germany
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GSK Investigational Site
RECRUITINGMannheim, 68167, Germany
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GSK Investigational Site
RECRUITINGBologna, 40138, Italy
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GSK Investigational Site
RECRUITINGCatania, 95123, Italy
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GSK Investigational Site
RECRUITINGFlorence, 50134, Italy
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GSK Investigational Site
RECRUITINGMeldola FC, 47014, Italy
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GSK Investigational Site
RECRUITINGMilan, 20122, Italy
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GSK Investigational Site
RECRUITINGRoma, 161, Italy
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GSK Investigational Site
RECRUITINGBadalona, 08005, Spain
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GSK Investigational Site
RECRUITINGBarcelona, 8035, Spain
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GSK Investigational Site
RECRUITINGLas Palmas, 35020, Spain
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GSK Investigational Site
RECRUITINGMadrid, 28009, Spain
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GSK Investigational Site
RECRUITINGMadrid, 28034, Spain
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GSK Investigational Site
RECRUITINGMálaga, 29010, Spain
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GSK Investigational Site
RECRUITINGValencia, 46026, Spain
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Conditions
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