Tumor DNA study aims to unlock secrets of drug resistance
NCT ID NCT03347318
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study collects tumor tissue, blood, and saliva from 2500 people with various solid cancers to analyze their genetic makeup. The goal is to understand why some tumors become resistant to targeted therapies. Samples may also be grown in special mice to study how genetics affect drug response. This is an observational study, meaning no new treatment is being tested.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand why some tumors stop responding to targeted drugs, potentially guiding future treatment choices.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly benefit participants, and the findings may not lead to immediate changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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A.O. Città della Salute e della Scienza di Torino - Presidio ospedaliero Ostetrico Ginecologico Sant'Anna
Turin, Italy
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AOU Città della Salute e della Scienza di Torino - Presidio Molinette
Turin, Italy
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AOU S. Luigi Gonzaga
Orbassano, Italy
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Azienda Ospedaliera Niguarda Ca'Granda
Milan, Italy
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Azienda Ospedaliero Universitaria Pisana
Pisa, Italy
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Azienda Ospedaliero-Universitaria Careggi
Genova, Italy
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Fondazione IRCCS - Istituto Nazionale dei Tumori
Milan, Italy
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IEO - Istiuto Europeo di Oncologia
Milan, Italy
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IOV - Istituto Oncologico Veneto
Padova, Italy
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Istituto Di Candiolo - Fondazione Del Piemonte Per L'Oncologia (FPO-Irccs)
Candiolo, Italy
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Ospedale Mauriziano Umberto I
Turin, Italy
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Ospedale Regionale Umberto Parini
Aosta, Italy
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Policlinico S.Orsola Malpighi
Bologna, Italy
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Policlinico Universitario Campus Biomedico
Roma, Italy
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Presidio Ospedaliero Martini
Turin, Italy
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