Moisturizer before rosacea cream? study checks if it helps or hurts

NCT ID NCT06434519

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether applying moisturizer before metronidazole cream changes how much medication gets into the skin of people with rosacea. Twenty-one adults had moisturizer and metronidazole applied to their face, then researchers used tape strips to measure drug levels after 1 and 4 hours. The goal is to see if the common practice of layering moisturizer affects treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
metronidazole cream
What this could lead to
If it works, this could guide rosacea patients on whether to apply moisturizer before or after their medication for better absorption.
What could go wrong
This is a small, completed study with only 21 participants. It measures skin absorption, not actual symptom improvement, so real-world benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

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Other studies related to the condition(s) this trial covers.