Could a Custom-Tailored therapy beat standard talk therapy for tough depression?

NCT ID NCT07380451

Recruiting now Symptom relief Sponsor: Pontificia Universidad Catolica de Chile Source: ClinicalTrials.gov ↗

First seen Feb 02, 2026 · Last updated May 13, 2026 · Updated 13 times

Summary

This study tests whether a personalized, algorithm-based psychotherapy is more effective than usual one-on-one therapy for adults with major depression complicated by personality problems or past trauma. About 150 people in Chile's public mental health system will be randomly assigned to either the new modular therapy or standard therapy. Researchers will track depression remission, symptom reduction, and daily mood changes to see which approach works better.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CDT CASR
RECRUITING

Santiago, Chile

Contact Phone: •••-•••-•••• Email: •••••@•••••
COSAM La Bandera
ACTIVE_NOT_RECRUITING

Santiago, Chile
COSAM La Granja
RECRUITING

Santiago, Chile

Contact Phone: •••-•••-•••• Email: •••••@•••••
COSAM La Pintana
RECRUITING

Santiago, Chile

Contact Phone: •••-•••-•••• Email: •••••@•••••
COSAM Rinconada
RECRUITING

Santiago, Chile

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

MAJOR DEPRESSION