Moderna tests mRNA shot to tame multiple sclerosis

NCT ID NCT06735248

Summary

This study is testing the safety and early effectiveness of an experimental mRNA injection called mRNA-1195 in adults with early-stage multiple sclerosis (MS). Researchers will give different doses or a placebo to 180 participants and monitor them for side effects and changes in brain lesions over nearly three years. The goal is to see if this new approach can help control the disease activity in people with MS.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ANESC Research

    RECRUITING

    El Paso, Texas, 79912, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Anne Rowling Regenerative Neurology Clinic, University of Edinburgh

    RECRUITING

    Edinburgh, EH16 4SB, United Kingdom

  • Boston Clinical Trials Inc - Internal Medicine

    RECRUITING

    Boston, Massachusetts, 02131, United States

  • Cambridge Clinical Research Centre

    RECRUITING

    London, CB2 0SL, United Kingdom

  • Cardiff and Vale University Health Board - University Hospital Wales

    RECRUITING

    Cardiff, CF14 4XW, United Kingdom

  • East Kent Hospitals University NHS Foundation Trust

    RECRUITING

    London, CT1 3NG, United Kingdom

  • NHS Greater Glasgow & Clyde - Institute of Neurological Sciences

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

  • North Bristol NHS Trust - Southmead Hospital

    RECRUITING

    Bristol, BS10 5NB, United Kingdom

  • Oklahoma Medical Research Foundation (OMRF) MS Center of Excellence

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • Quest Research Institute

    RECRUITING

    Farmington Hills, Michigan, 48334, United States

  • Saturn Research Solutions

    RECRUITING

    Plano, Texas, 75024, United States

  • Sharlin Health & Neurology

    RECRUITING

    Ozark, Missouri, 65721, United States

  • Sheffield Teaching Hospital NHS foundation Trust, Herries Road

    RECRUITING

    Sheffield, S10 2JF, United Kingdom

  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust

    RECRUITING

    Newcastle upon Tyne, NE14LP, United Kingdom

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390-8806, United States

  • University of the Sunshine Coast Clinical Trials

    RECRUITING

    Birtinya, Queensland, 04575, Australia

  • Washington University School of Medicine Neurology Clinical Unit

    RECRUITING

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.