New drug trial halted after testing in advanced cancer patients

NCT ID NCT04157517

Summary

This early-phase study tested the safety and initial effectiveness of a new drug called modakafusp alfa, both alone and combined with an existing immunotherapy (pembrolizumab), in adults with advanced solid tumors or melanoma. The main goals were to find a safe dose and check for side effects. The study was terminated early and enrolled a limited number of participants.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Avera Cancer Institute

    Sioux Falls, South Dakota, 57105, United States

  • Ballarat Regional Integrated Cancer Center

    Ballarat, Victoria, 3350, Australia

  • City of Hope Comprehensive Cancer Center - Duarte

    Duarte, California, 91010, United States

  • Cleveland Clinic Main Campus

    Cleveland, Ohio, 44195, United States

  • Intermountain Medical Center

    Murray, Utah, 84107, United States

  • Morristown Medical Center

    Morristown, New Jersey, 07960, United States

  • Norris Cotton Cancer Center Lebanon

    Lebanon, New Hampshire, 03756, United States

  • Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • Texas Oncology - Baylor Charles A. Sammons Cancer Center

    Dallas, Texas, 75246, United States

  • The Angeles Clinic and Research Institute - West Los Angeles Office

    Los Angeles, California, 90025, United States

  • The Queen Elizabeth Hospital

    Woodville South, South Australia, 5011, Australia

  • University of California San Diego Moores Cancer Center

    La Jolla, California, 92093, United States

  • University of Colorado Health Memorial Hospital Central

    Colorado Springs, Colorado, 80909, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15232, United States

  • West Virginia University Health Sciences Campus

    Morgantown, West Virginia, 26506, United States

Conditions

Explore the condition pages connected to this study.