New combo therapy shows promise for rare sarcomas

NCT ID NCT02406781

Completed Disease control Sponsor: Institut Bergonié Source: ClinicalTrials.gov ↗

First seen Jan 05, 2026 · Last updated May 15, 2026 · Updated 20 times

Summary

This study tested a combination of two drugs (MK3475 and cyclophosphamide) in 129 people with advanced sarcomas that could not be removed by surgery or had spread. The goal was to see if the treatment could shrink tumors or stop them from growing for at least 6 months. The trial included different types of sarcomas to see which might benefit most.

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Contacts and locations

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Locations

Centre Léon Bérard

Lyon, 69373, France
Centre Oscar Lambret

Lille, 59020, France
Institut Bergonié

Bordeaux, 33076, France
Institut Claudius Regaud

Toulouse, 31052, France
Institut Curie

Paris, 75005, France
Institut Gustave Roussy

Villejuif, 94800, France
Institut Paoli Calmettes

Marseille, 13273, France
Institut de Cancérologie de l'Ouest

Saint-Herblain, 44805, France

Conditions

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SARCOMA