New Alzheimer's drug shows promise for agitation and psychosis

NCT ID NCT05227118

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested the safety of a new drug called MK-8189 (elpipodect) in 29 people with Alzheimer's disease who also had symptoms like agitation, aggression, or psychosis. The main goal was to see if the drug was safe and tolerable. Researchers monitored side effects and how many people stopped the study due to side effects.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atlanta Center for Medical Research ( Site 0004)

    Atlanta, Georgia, 30331, United States

  • CITrials ( Site 0007)

    Santa Ana, California, 92705, United States

  • Global Medical Institutes LLC; Princeton Medical Institute ( Site 0008)

    Princeton, New Jersey, 08540, United States

  • Richmond Behavioral Associates ( Site 0003)

    Staten Island, New York, 10314, United States

  • Top Medical Research ( Site 0005)

    Cutler Bay, Florida, 33189, United States

  • Velocity Clinical Research, Hallandale Beach ( Site 0001)

    Hallandale, Florida, 33009, United States

  • Well Pharma Medical Research, Corp. ( Site 0006)

    Miami, Florida, 33173, United States

  • iResearch Atlanta ( Site 0009)

    Decatur, Georgia, 30030, United States