New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT02964013

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 26 times

Summary

This early-phase study tested a new drug called vibostolimab (MK-7684), either alone or combined with pembrolizumab and other chemotherapy drugs, in adults with advanced solid tumors that had no standard treatment options. The main goals were to check safety, find the right dose, and see if the drug shrinks tumors. The study involved 474 participants and is now complete.

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