New hope for japanese men with tough prostate cancer?

NCT ID NCT06104449

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tested a new drug, opevesostat (MK-5684), in 7 Japanese men with a type of advanced prostate cancer that no longer responds to standard hormone therapy. The main goals were to check the drug's safety and how the body processes it. This is a first step to see if the drug might help control the disease.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma prostate cancer prostate neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Cancer Center Hospital East ( Site 0001)

    Kashiwa, Chiba, 277-8577, Japan

  • Toho University Sakura Medical Center ( Site 0003)

    Sakura, Chiba, 285-8741, Japan

  • Yokohama City University Medical Center ( Site 0002)

    Yokohama, Kanagawa, 232-0024, Japan