New shot shows promise for tough skin cancer in japanese patients

NCT ID NCT06041802

First seen Dec 29, 2025 · Last updated Apr 28, 2026 · Updated 19 times

Summary

This study tests a new drug combination (pembrolizumab plus hyaluronidase) given as a shot under the skin for Japanese patients with advanced skin cancer that has spread or cannot be removed by surgery. The goal is to see if the drug can shrink tumors and control the disease. About 19 participants will be enrolled, and the study focuses on safety and how well the treatment works.

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Contacts and locations

Locations

  • Cancer Institute Hospital of JFCR ( Site 0018)

    Koto, Tokyo, 135-8550, Japan

  • Chiba University Hospital ( Site 0001)

    Chiba, 260-8677, Japan

  • Keio University Hospital ( Site 0010)

    Tokyo, 1608582, Japan

  • Nagoya University Hospital ( Site 0003)

    Nagoya, Aichi-ken, 466-8560, Japan

  • National Cancer Center Hospital ( Site 0007)

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Hospital Organization Kagoshima Medical Center ( Site 0013)

    Kagoshima, 892-0853, Japan

  • National Hospital Organization Kyushu Cancer Center ( Site 0017)

    Fukuoka, 811-1395, Japan

  • Niigata Cancer Center Hospital ( Site 0005)

    Niigata, Niigata, 951-8566, Japan

  • Osaka Prefectural Hospital Organization Osaka International Cancer Institute ( Site 0009)

    Osaka, 541-8567, Japan

  • Saitama Medical University International Medical Center ( Site 0008)

    Hidaka, Saitama, 350-1298, Japan

  • Sapporo Medical University Hospital ( Site 0002)

    Sapporo, Hokkaido, 060-8543, Japan

  • Shimane University Hospital ( Site 0014)

    Izumo, Shimane, 693-8501, Japan

  • Shinshu University Hospital ( Site 0011)

    Matsumoto, Nagano, 390-8621, Japan

  • Shizuoka Cancer Center ( Site 0004)

    Nagaizumi-cho,Sunto-gun, Shizuoka, 411-8777, Japan

  • Tohoku University Hospital ( Site 0019)

    Sendai, Miyagi, 980-8574, Japan

  • University Hospital,Kyoto Prefectural University of Medicine ( Site 0012)

    Kyoto, 602-8566, Japan

  • Wakayama Medical University Hospital ( Site 0015)

    Wakayama, 641-8510, Japan

  • Yokohama City University Hospital ( Site 0016)

    Yokohama, Kanagawa, 236-0004, Japan

Conditions

Explore the condition pages connected to this study.