New Alzheimer's drug combo shows promise in Mid-Stage trial
NCT ID NCT06721156
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 20 times
Summary
This study tests whether adding MK-1167 to standard Alzheimer's medication can improve memory and thinking in people with mild to moderate Alzheimer's dementia. About 350 participants will receive either MK-1167 or a placebo for 24 weeks. The main goals are to see if the drug improves cognitive test scores and to check its safety and tolerability.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Anderson Clinical Research ( Site 0164)
Redlands, California, 92374, United States
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Aqualane Clinical Research ( Site 0116)
Naples, Florida, 34105, United States
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Asan Medical Center ( Site 1603)
Seoul, 05505, South Korea
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Association of Healthcare Corporation Koukankai Koukan Clinic ( Site 1510)
Kawasaki, Kanagawa, 210-0852, Japan
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Banner Alzheimer's Institute ( Site 0110)
Phoenix, Arizona, 85006, United States
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Brain Matters Research ( Site 0151)
Stuart, Florida, 34997, United States
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Brain Matters Research-Neurology ( Site 0150)
Delray Beach, Florida, 33445, United States
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Brain Research Center Den Bosch B.V. ( Site 1002)
's-Hertogenbosch, North Brabant, 5223 LA, Netherlands
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Brain Research Center Zwolle ( Site 1003)
Zwolle, Overijssel, 8025 AZ, Netherlands
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Brain Research Center. ( Site 1001)
Amsterdam, North Holland, 1081 GN, Netherlands
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Brain Sciences Scotland Life Sciences-Aberdeen ( Site 1402)
Aberdeen, Aberdeen City, AB25 2XE, United Kingdom
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California Neuroscience Research ( Site 0118)
Sherman Oaks, California, 91403, United States
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Campus for Ageing and Vitality ( Site 1408)
Newcastle upon Tyne, NE4 5PL, United Kingdom
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CenExel iResearch, LLC ( Site 0134)
Savannah, Georgia, 31405, United States
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Centro S Giovanni Di Dio Fatebenefratelli ( Site 0904)
Brescia, 25125, Italy
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Centro de Atención Especializada Oroitu ( Site 1211)
Algorta, Bizkaia, 48993, Spain
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Columbus Memory Center ( Site 0197)
Columbus, Georgia, 31909, United States
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Enomoto Internal Medicine Clinic(Chofu) ( Site 1503)
Chōfu, Tokyo, 182-0036, Japan
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Flourish Research - Charlotte ( Site 0106)
Matthews, North Carolina, 28105, United States
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Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico-UOSD Malattie Neurodegenerative ( Site 0903)
Milan, Lombardy, 20122, Italy
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Fondazione IRCCS San Gerardo dei Tintori ( Site 0902)
Monza, Monza E Brianza, 20900, Italy
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 0905)
Roma, 00168, Italy
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Fundació ACE ( Site 1206)
Barcelona, 08034, Spain
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Grayline Research Center ( Site 0105)
Wichita Falls, Texas, 76309, United States
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Hanyang University Seoul Hospital ( Site 1605)
Seoul, 04763, South Korea
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Hatsuta Neurology Clinic ( Site 1507)
Hirakata, Osaka, 573-1121, Japan
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Headlands Research Orlando ( Site 0169)
Orlando, Florida, 32806, United States
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Hospital Italiano de Buenos Aires ( Site 0209)
Buenos Aires, Buenos Aires F.D., C1199ABD, Argentina
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Hospital Universitari Vall D Hebron ( Site 1203)
Barcelona, 08035, Spain
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Hospital Universitari i Politecnic La Fe ( Site 1202)
Valencia, Valencia, 46026, Spain
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Hospital Universitario 12 de Octubre ( Site 1208)
Madrid, Madrid, Comunidad de, 28041, Spain
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Hospital Universitario Virgen de la Macarena ( Site 1210)
Seville, 41009, Spain
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Hospital de la Santa Creu i Sant Pau ( Site 1204)
Barcelona, Catalonia, 8025, Spain
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Indago Research & Health Center, Inc ( Site 0128)
Hialeah, Florida, 33012, United States
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Inha University Hospital ( Site 1601)
Incheon, 22332, South Korea
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Instituto Geriatrico Nuestra Señora de Las Nieves ( Site 0208)
Buenos Aires, Buenos Aires F.D., C1427CCP, Argentina
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Instituto Kremer ( Site 0202)
Córdoba, X5004AOA, Argentina
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Instituto de Investigaciones Clínicas Mar del Plata ( Site 0207)
Mar del Plata, Buenos Aires, B7600FZN, Argentina
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Irvine Clinical Research ( Site 0104)
Irvine, California, 92614, United States
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Itsuki Hospital ( Site 1502)
Tokushima, 770-0852, Japan
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Iwaki Clinic ( Site 1518)
Anan, Tokushima, 774-0014, Japan
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JEM Research Institute / Headlands Research Network ( Site 0108)
Atlantis, Florida, 33462, United States
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K2 Medical Research ( Site 0103)
Maitland, Florida, 32750, United States
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K2 Medical Research ( Site 0165)
Tampa, Florida, 33634, United States
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K2 Medical Research THE VILLAGES ( Site 0166)
Lady Lake, Florida, 32159, United States
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Kawasaki Saiwai Clinic ( Site 1501)
Kawasaki, Kanagawa, 212-0016, Japan
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Kerwin Medical Center ( Site 0159)
Dallas, Texas, 75231, United States
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Mid Hudson Medical Research ( Site 0191)
New Windsor, New York, 12553, United States
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Moorgreen Hospital ( Site 1409)
Southampton, Hampshire, SO30 3JB, United Kingdom
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Nagomi Clinic ( Site 1506)
Toyonaka, Osaka, 560-0004, Japan
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Neuropsychiatric Research Center of Southwest Florida ( Site 0152)
Fort Myers, Florida, 33912, United States
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Northwest Clinical Research Center ( Site 0102)
Bellevue, Washington, 98007, United States
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Nozomi Memory Clinic ( Site 1504)
Mitaka, Tokyo, 181-0013, Japan
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Okanagan Clinical Trials ( Site 0001)
Kelowna, British Columbia, V1Y 1Z9, Canada
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Organizacion Medica de Investigacion - OMI S.A. ( Site 0204)
Buenos Aires, C1015ABO, Argentina
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Ospedale San Raffaele. ( Site 0901)
Milan, 20132, Italy
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Ottawa Memory Clinic ( Site 0004)
Ottawa, Ontario, K1Z 1G3, Canada
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Pharmasite Research, Inc. ( Site 0167)
Baltimore, Maryland, 21208, United States
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Premier Clinical Research Institute ( Site 0114)
Miami, Florida, 33122, United States
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Quest Research Institute ( Site 0173)
Farmington Hills, Michigan, 48334, United States
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Re:Cognition Health - Birmingham ( Site 1406)
Birmingham, B16 8LT, United Kingdom
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Remind UK ( Site 1404)
Bath, Somerset, BA1 3NG, United Kingdom
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Scottish Brain Sciences ( Site 1401)
Edinburgh, Edinburgh, City of, EH12 5PJ, United Kingdom
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Seoul National University Hospital ( Site 1604)
Seoul, 03080, South Korea
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Summit Research Network ( Site 0111)
Portland, Oregon, 97210, United States
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Takesato Hospital ( Site 1522)
Kasukabe, Saitama, 344-0036, Japan
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Tandem Clinical Research ( Site 0101)
Marrero, Louisiana, 70072, United States
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Tokyo Metropolitan Institute for Geriatrics and Gerontology ( Site 1515)
tabashi City, Tokyo, 173-0015, Japan
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Toronto Memory Program ( Site 0006)
Toronto, Ontario, M3B 2S7, Canada
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Velocity Clinical Research - Raleigh ( Site 0123)
Raleigh, North Carolina, 27607, United States
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Velocity Clinical Research, Syracuse ( Site 0125)
East Syracuse, New York, 13057, United States
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Windsor Research Unit ( Site 1403)
Cambridge, CB21 5EF, United Kingdom
Conditions
Explore the condition pages connected to this study.