New clip fixes leaky heart valve without open surgery
NCT ID NCT04259411
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the MitraClip device in 51 people in China with a leaky heart valve (mitral regurgitation). The device is inserted through a vein in the leg and clips the valve to reduce leakage. The goal was to see if the procedure is safe and effective, with recovery typically taking two to three days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MitraClip device (a catheter-based clip to repair the mitral valve)
- What this could lead to
- If successful, this could offer a less invasive treatment option for people with mitral regurgitation, reducing symptoms and improving daily life without open-heart surgery.
- What could go wrong
- This was a small, single-arm study with no comparison group, so results may not apply broadly. Risks include procedural complications like stroke or heart attack.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Fuwai Hospital Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China
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Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
Shenzhen, Guangdong, China
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The 2nd Affiliated Hospital of Zhejiang University
Hangzhou, Zhejiang, 310009, China
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The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China
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Xiamen Cardiovascular Hospital Xiamen University
Xiamen, Fujian, 361008, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New heart valve device could spare High-Risk patients from Open-Heart surgery
- First-in-Human trial aims to offer new hope for patients with leaky heart valves who Can't have surgery
- Wireless sensor could help doctors Fine-Tune heart failure treatment in real time
- Tiny device could fix leaky heart valves without cutting chest open
- Artificial intelligence could make heart valve surgery safer and more precise
- Experimental heart valve device tested in just one patient — study halted