New scan spots chemo damage to heart and muscles early

NCT ID NCT05731375

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special MRI scan (31P-MRS) can detect early signs of damage to heart and muscle cells caused by chemotherapy drugs like doxorubicin. Twelve cancer patients scheduled for chemo underwent three scans over time. The goal was to see if the scan could measure changes in energy production inside cells, which might help doctors catch problems before they become serious.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a non-invasive way to detect early chemotherapy-related heart and muscle damage, helping doctors adjust treatment sooner.

What could go wrong

This is a very small, completed observational study with only 12 participants. It does not test any treatment, so it may not lead to direct patient benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer cardiomyopathy due to anthracyclines chemotherapy-induced toxicity doxorubicin induced cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Diakonessenhuis

    Utrecht, Utrecht, 3582 KE, Netherlands

  • Meander Medisch Centrum

    Amersfoort, Utrecht, 3813 TZ, Netherlands

  • UMC Utrecht

    Utrecht, Utrecht, 3584CX, Netherlands

  • Ziekenhuis Gelderse Vallei

    Ede, Gelderland, 6716 RP, Netherlands