Could a simple pill improve uterine niche surgery outcomes?

NCT ID NCT07271056

Completed Symptom relief Sponsor: Benha University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking misoprostol under the tongue two hours before surgery for uterine niche (a scar complication after C-section) helps reduce postmenstrual spotting. Fifty-six women with prior C-section and abnormal bleeding were randomly assigned to receive misoprostol or a placebo. The goal was to see if the drug makes the surgery safer and more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: misoprostol
What this could lead to: If it works, this could offer a simple way to improve recovery and reduce bleeding after surgery for uterine niche.
What could go wrong: This is a small, completed trial with only 56 participants, so results may not apply to everyone. Misoprostol can cause side effects like cramping or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Metrorrhagia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABNORMAL UTERINE BLEEDING CESAREAN SECTION COMPLICATIONS SCAR NICHE

Contacts and locations

Locations

Benha Univesity Hospital

Banhā, Qalyubia Governorate, 13512, Egypt

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