Could a simple pill improve uterine niche surgery outcomes?
NCT ID NCT07271056
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking misoprostol under the tongue two hours before surgery for uterine niche (a scar complication after C-section) helps reduce postmenstrual spotting. Fifty-six women with prior C-section and abnormal bleeding were randomly assigned to receive misoprostol or a placebo. The goal was to see if the drug makes the surgery safer and more effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
misoprostol
What this could lead to
If it works, this could offer a simple way to improve recovery and reduce bleeding after surgery for uterine niche.
What could go wrong
This is a small, completed trial with only 56 participants, so results may not apply to everyone. Misoprostol can cause side effects like cramping or nausea.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Benha Univesity Hospital
Banhā, Qalyubia Governorate, 13512, Egypt