Can a simple pill make fibroid surgery safer?
NCT ID NCT07286188
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving misoprostol (a drug often used for stomach ulcers and labor) before hysteroscopic fibroid removal can reduce the amount of fluid absorbed by the body during surgery. Too much fluid can be dangerous. Forty women with small fibroids (1-3 cm) will receive either misoprostol or a placebo rectally before their procedure. The main goal is to see if misoprostol lowers fluid deficit, with secondary looks at surgery time and need for repeat procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
misoprostol
What this could lead to
If it works, this could help reduce the risk of fluid overload during hysteroscopic fibroid surgery, making the procedure safer.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply widely. Misoprostol may not reduce fluid deficit or could cause side effects like cramping or nausea.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HYSTEROSCOPY / METHODS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Email: •••••@•••••
Locations
-
Northwestern
RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••